ZNF610

Across TCGA cell cohorts, ZNF610 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,211 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF610-associated GO terms across cancer lineages are Negative regulation of transcription by RNA polymerase I, COPII vesicle coating, and Chromosomal 5-methylcytosine DNA demethylation pathway. Each is linked with ZNF610 in more than 8 cancer types. Because this analysis shows association rather than direction, both ZNF610-to-partner and partner-to-ZNF610 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of transcription by RNA polymerase I grouped by ZNF610-low versus ZNF610-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF610→partner) and Y-score (partner→ZNF610) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Negative regulation of transcription by RNA polymerase I →	+0.117	+0.665	<.001	.003	3	9
LUNG_SCLC	COPII vesicle coating →	+0.120	+1.826	<.001	<.001	3	9
LIVER	Chromosomal 5-methylcytosine DNA demethylation pathway →	+0.149	+1.142	<.001	<.001	3	8
LUNG_SCLC	Peptidyl-lysine acetylation →	+0.122	+1.351	<.001	<.001	3	8
KIDNEY	Negative regulation of myoblast fusion →	+0.090	+0.791	<.001	.001	3	8
LUNG_SCLC	Regulation of stem cell population maintenance →	+0.088	+1.823	.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,211 associations by consensus.

Negative regulation of transcription by RNA polymerase I by ZNF610 expression — SOFT_TISSUE

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