ZNF610

Across TCGA cell cohorts, ZNF610 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF610-associated genes across cancer lineages are CALHM4, SPEM3, and PF4. Each is linked with ZNF610 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF610-to-partner and partner-to-ZNF610 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CALHM4 grouped by ZNF610-low versus ZNF610-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF610→partner) and Y-score (partner→ZNF610) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CALHM4 →	+0.038	+5.269	<.001	<.001	3	1
BLOOD_Leukemia	SPEM3 →	+0.013	+4.409	<.001	.005	3	1
BLOOD_Lymphoma	PF4 →	+0.044	+4.867	<.001	.009	3	1
LARGE_INTESTINE	MMP26 →	+0.039	+3.632	<.001	.003	3	1
LARGE_INTESTINE	C10orf53 →	+0.012	+3.632	<.001	.003	3	1
SKIN	KRTAP5-11 →	+0.032	+3.684	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

CALHM4 by ZNF610 expression — BLOOD_Leukemia

Explore this box plot interactively →