ZNF609

Across TCGA patient cohorts, ZNF609 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,302 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF609-associated proteins across cancer lineages are ZNF609_S491, TP53BP1, and CACNA2D1. Each is linked with ZNF609 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZNF609-to-partner and partner-to-ZNF609 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF609 versus ZNF609_S491 in GBM, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF609→partner) and Y-score (partner→ZNF609) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ZNF609_S491 →	+0.586	+0.462	<.001	.001	3	7
GBM	TP53BP1 →	+0.281	+0.507	.004	.001	3	5
GBM	CACNA2D1 →	+0.582	+0.417	.001	<.001	3	4
LSCC	ZNF609_S576 →	+0.447	+0.633	<.001	<.001	3	4
GBM	ZNF609_S758 →	+0.591	+0.519	<.001	<.001	3	4
PDAC	TP53BP1_S500 →	+0.631	+0.349	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,302 associations by consensus.

ZNF609 vs ZNF609_S491 — GBM

Explore this scatter interactively →