ZNF609

Across TCGA patient cohorts, ZNF609 protein abundance is significantly associated with the RNA expression of many other genes, with 13,221 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF609-associated genes across cancer lineages are ICE2, PATZ1, and CLK3. Each is linked with ZNF609 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZNF609-to-partner and partner-to-ZNF609 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF609 versus ICE2 in HNSC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF609→partner) and Y-score (partner→ZNF609) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ICE2 →	+0.559	+0.263	<.001	<.001	3	7
UCEC	PATZ1 →	+0.872	+0.316	<.001	<.001	3	6
HNSC	CLK3 →	+0.441	+0.270	<.001	<.001	3	6
BRCA	DIDO1 →	+0.505	+0.323	.001	.001	3	5
LSCC	BCL7A →	+0.968	+0.359	<.001	<.001	3	5
LSCC	RIC8B →	+0.660	+0.381	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,221 associations by consensus.

ZNF609 vs ICE2 — HNSC

Explore this scatter interactively →