Across TCGA patient cohorts, ZNF605 mutation is significantly associated with the RNA expression of many other genes, with 1,907 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF605-associated genes across cancer lineages are MIR6882, MIR4708, and MIR26A1. Each is linked with ZNF605 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF605-to-partner and partner-to-ZNF605 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF605→partner) and Y-score (partner→ZNF605) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MIR6882 →	+0.593	+4.995	<.001	<.001	3	3
BRCA	MIR4708 →	+0.515	+7.731	<.001	.009	3	2
HNSC	MIR26A1 →	+0.452	+4.449	<.001	.002	3	2
HNSC	RNA5SP256 →	+0.252	+4.310	.004	.002	3	2
HNSC	RNU6-1246P →	+0.267	+5.178	<.001	.002	3	2
HNSC	SOD1P1 →	+0.109	+3.716	.003	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,907 associations by consensus.

Exploration

ZNF605 survival (RNA) · tumor vs normal (RNA) · all ZNF605 data types