Q-omics provides the consensus-scored ZNF603P profile across patient tissues and cancer cell-line models. ZNF603P expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, ZNF603P is differentially expressed in 5, with the highest sampling consensus in KICH. Additionally, ZNF603P RNA expression shows 11,307 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight KIRC, KICH, and THYM as cancer lineages where ZNF603P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for ZNF603P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes ZNF603P survival associations across molecular data types. ZNF603P RNA expression shows survival associations in the most cancer types (18). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible ZNF603P RNA expression–survival associations across cancer types. High ZNF603P expression shows unfavorable associations in KIRC, DLBC, LIHC and ACC, but favorable associations in UVM and BLCA. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for ZNF603P RNA expression.
This table summarizes ZNF603P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in KICH for RNA.
This table ranks reproducible tumor–normal expression differences for ZNF603P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. ZNF603P shows lower tumor expression in KICH, COAD, BRCA and PAAD and higher tumor expression in CHOL. The KICH box plot shows higher ZNF603P RNA expression in normal versus tumor tissue (log2 FC = −0.333, t-test p = .001).
This table shows molecular features associated with ZNF603P in patient tissues and cancer cell lines. In patient samples, ZNF603P shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
