Across TCGA cell cohorts, ZNF600 mutation is significantly associated with the RNA expression of many other genes, with 385 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF600-associated genes across cancer lineages are GUCA1C, TNRC6B, and HSPA8. Each is linked with ZNF600 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF600-to-partner and partner-to-ZNF600 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF600→partner) and Y-score (partner→ZNF600) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GUCA1C →	+0.029	+4.969	<.001	.003	3	1
LARGE_INTESTINE	TNRC6B →	+0.870	+3.212	<.001	.006	3	1
LARGE_INTESTINE	HSPA8 →	+0.747	+3.212	.004	.006	3	1
LARGE_INTESTINE	CDKN1B →	+0.783	+3.212	.003	.006	3	1
LARGE_INTESTINE	NCOA7 →	+1.367	+3.299	.001	.004	3	1
LARGE_INTESTINE	FOXP1 →	+1.428	+3.212	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 385 associations by consensus.

Exploration

ZNF600 survival (RNA) · tumor vs normal (RNA) · all ZNF600 data types