ZNF597

Across TCGA patient cohorts, ZNF597 mutation is significantly associated with the RNA expression of many other genes, with 788 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF597-associated genes across cancer lineages are C16orf95, MIR519D, and LINC02876. Each is linked with ZNF597 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF597-to-partner and partner-to-ZNF597 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C16orf95 grouped by ZNF597-low versus ZNF597-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF597→partner) and Y-score (partner→ZNF597) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	C16orf95 →	+0.438	+3.251	<.001	.008	3	2
CESC	MIR519D →	+0.492	+6.342	<.001	.001	3	2
CESC	LINC02876 →	+0.056	+5.010	.002	.009	3	2
UCEC	CCL5 →	+1.054	+3.021	.004	<.001	3	2
UCEC	CCL4 →	+0.747	+3.021	.009	<.001	3	2
UCEC	CIDECP1 →	+0.518	+2.823	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 788 associations by consensus.

C16orf95 by ZNF597 expression — COAD

Explore this box plot interactively →