ZNF597

Across TCGA cell cohorts, ZNF597 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,193 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF597-associated GO terms across cancer lineages are N-terminal protein amino acid acetylation, Symbiont-mediated disruption of host cell PML body, and Regulation of gene silencing by regulatory ncRNA. Each is linked with ZNF597 in more than 14 cancer types. Because this analysis shows association rather than direction, both ZNF597-to-partner and partner-to-ZNF597 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, N-terminal protein amino acid acetylation grouped by ZNF597-low versus ZNF597-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF597→partner) and Y-score (partner→ZNF597) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	N-terminal protein amino acid acetylation →	+0.148	+0.839	<.001	<.001	3	15
LARGE_INTESTINE	Symbiont-mediated disruption of host cell PML body →	+0.103	+0.737	<.001	<.001	3	7
BREAST	Regulation of gene silencing by regulatory ncRNA →	+0.081	+0.830	<.001	<.001	3	7
KIDNEY	Regulation of aggrephagy →	+0.106	+0.323	.002	.006	2	8
LARGE_INTESTINE	Regulation of mitotic cytokinetic process →	+0.104	+0.604	<.001	<.001	3	6
LARGE_INTESTINE	Positive regulation of mitotic cytokinetic process →	+0.104	+0.604	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,193 associations by consensus.

N-terminal protein amino acid acetylation by ZNF597 expression — BREAST

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