ZNF597

Across TCGA cell cohorts, ZNF597 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF597-associated genes across cancer lineages are IQCF5, RGS21, and MYF6. Each is linked with ZNF597 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF597-to-partner and partner-to-ZNF597 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IQCF5 grouped by ZNF597-low versus ZNF597-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF597→partner) and Y-score (partner→ZNF597) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	IQCF5 →	+0.079	+4.058	<.001	.009	3	2
BLOOD_Leukemia	RGS21 →	+0.044	+4.539	<.001	.007	3	2
PANCREAS	MYF6 →	+0.006	+5.614	<.001	.002	3	1
CNS	KNCN →	+0.033	+3.459	<.001	.006	3	1
CNS	HPGDS →	+0.042	+4.369	<.001	<.001	3	1
CNS	NUPR2 →	+0.050	+3.459	.003	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

IQCF5 by ZNF597 expression — BLOOD_Lymphoma

Explore this box plot interactively →