ZNF596

Across TCGA cell cohorts, ZNF596 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,058 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF596-associated GO terms across cancer lineages are Regulation of telomere capping, Cilium movement involved in cell motility, and Cilium or flagellum-dependent cell motility. Each is linked with ZNF596 in more than 17 cancer types. Because this analysis shows association rather than direction, both ZNF596-to-partner and partner-to-ZNF596 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of telomere capping grouped by ZNF596-low versus ZNF596-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF596→partner) and Y-score (partner→ZNF596) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of telomere capping →	+0.131	+0.956	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.107	-0.804	<.001	.001	3	17
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.093	-0.644	<.001	.002	3	16
SOFT_TISSUE	Positive regulation of telomere capping →	+0.122	+1.059	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.093	-0.644	<.001	.002	3	16
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.104	-0.857	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,058 associations by consensus.

Regulation of telomere capping by ZNF596 expression — URINARY_TRACT

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