ZNF596

Across TCGA cell cohorts, ZNF596 mutation is significantly associated with the mutation status of many other genes, with 1,719 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF596-associated genes across cancer lineages are NCAPD2, LACTB, and AP3B2. Each is linked with ZNF596 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF596-to-partner and partner-to-ZNF596 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NCAPD2 grouped by ZNF596-low versus ZNF596-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF596→partner) and Y-score (partner→ZNF596) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	NCAPD2 →	+2.289	+3.182	.008	.008	1	2
LARGE_INTESTINE	LACTB →	+3.459	+3.459	.006	.006	1	2
LARGE_INTESTINE	AP3B2 →	+3.459	+4.954	<.001	<.001	1	2
LARGE_INTESTINE	PIK3CG →	+2.781	+4.504	<.001	<.001	1	2
LARGE_INTESTINE	DNTT →	+4.044	+3.744	.003	.003	1	2
LARGE_INTESTINE	GNRHR →	+5.459	+4.744	<.001	<.001	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,719 associations by consensus.

NCAPD2 by ZNF596 expression — LARGE_INTESTINE

Explore this box plot interactively →