ZNF594

Across TCGA cell cohorts, ZNF594 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,269 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF594-associated GO terms across cancer lineages are Regulation of mRNA processing, mRNA transport, and Nuclear export. Each is linked with ZNF594 in more than 16 cancer types. Because this analysis shows association rather than direction, both ZNF594-to-partner and partner-to-ZNF594 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mRNA processing grouped by ZNF594-low versus ZNF594-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF594→partner) and Y-score (partner→ZNF594) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of mRNA processing →	+0.130	+1.243	<.001	<.001	3	17
BONE	mRNA transport →	+0.102	+0.996	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Nuclear export →	+0.129	+1.180	<.001	<.001	3	17
SOFT_TISSUE	Nuclear transport →	+0.095	+1.271	<.001	<.001	3	17
LUNG_SCLC	Positive regulation of transcription initiation by RNA polymerase II →	+0.085	+1.541	<.001	<.001	3	17
PANCREAS	DNA-templated transcription initiation →	+0.066	+0.960	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,269 associations by consensus.

Regulation of mRNA processing by ZNF594 expression — UPPER_AERODIGESTIVE_TRACT

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