ZNF592

Across TCGA cell cohorts, ZNF592 mutation is significantly associated with the RNA expression of many other genes, with 79 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF592-associated genes across cancer lineages are PRR27, OR5B21, and CA6. Each is linked with ZNF592 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF592-to-partner and partner-to-ZNF592 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRR27 grouped by ZNF592-low versus ZNF592-high in LIVER.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF592→partner) and Y-score (partner→ZNF592) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	PRR27 →	+0.025	+4.459	<.001	.001	3	2
BLOOD_Leukemia	OR5B21 →	+0.075	+3.781	.002	.004	3	2
LIVER	CA6 →	+0.162	+4.459	.002	.001	3	1
LIVER	DRD5 →	+0.077	+3.977	<.001	.006	3	1
LIVER	GPR141 →	+0.397	+4.459	<.001	.001	3	1
LIVER	KRTAP10-4 →	+0.017	+4.459	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 79 associations by consensus.

PRR27 by ZNF592 expression — LIVER

Explore this box plot interactively →