ZNF589

Across TCGA patient cohorts, ZNF589 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,800 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF589-associated proteins across cancer lineages are QRICH1, DHX30, and TOP2B. Each is linked with ZNF589 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZNF589-to-partner and partner-to-ZNF589 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF589 versus QRICH1 in GBM, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF589→partner) and Y-score (partner→ZNF589) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	QRICH1 →	+0.243	+0.480	<.001	<.001	3	7
GBM	DHX30 →	+0.244	+0.495	<.001	<.001	3	6
GBM	TOP2B →	+0.422	+0.487	<.001	<.001	3	6
LSCC	UNC13D →	-0.375	-0.487	<.001	<.001	3	5
GBM	SAP130 →	+0.211	+0.397	<.001	<.001	3	5
GBM	HNRNPA0 →	+0.365	+0.464	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,800 associations by consensus.

ZNF589 vs QRICH1 — GBM

Explore this scatter interactively →