ZNF589

Across TCGA patient cohorts, ZNF589 protein abundance is significantly associated with the RNA expression of many other genes, with 1,364 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF589-associated genes across cancer lineages are ABI3, SLC15A3, and TMEM255B. Each is linked with ZNF589 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF589-to-partner and partner-to-ZNF589 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF589 versus ABI3 in GBM, with a Pearson correlation of -0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF589→partner) and Y-score (partner→ZNF589) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ABI3 →	-1.013	-0.692	.003	.003	3	2
GBM	SLC15A3 →	-1.002	-0.984	.001	<.001	3	2
GBM	TMEM255B →	-0.630	-0.752	.001	.004	3	2
UCEC	OTUB2 →	+1.184	+0.461	<.001	<.001	3	2
LSCC	PAK5 →	+2.358	+1.759	<.001	.002	3	1
LSCC	CEP76 →	+0.956	+1.719	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,364 associations by consensus.

ZNF589 vs ABI3 — GBM

Explore this scatter interactively →