ZNF589

Across TCGA cell cohorts, ZNF589 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,684 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ZNF589-associated GO terms across cancer lineages are RNA catabolic process, Nucleic acid catabolic process, and Positive regulation of monoatomic ion transport. Each is linked with ZNF589 in more than 15 cancer types. Because this analysis shows association rather than direction, both ZNF589-to-partner and partner-to-ZNF589 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA catabolic process grouped by ZNF589-low versus ZNF589-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF589→partner) and Y-score (partner→ZNF589) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	RNA catabolic process →	+0.075	+1.854	<.001	<.001	3	16
BONE	Nucleic acid catabolic process →	+0.068	+1.519	<.001	<.001	3	15
BONE	Positive regulation of monoatomic ion transport →	-0.125	-1.056	<.001	<.001	3	14
BONE	Aminoacyl-tRNA metabolism involved in translational fidelity →	+0.137	+1.881	<.001	<.001	3	14
BONE	Positive regulation of DNA metabolic process →	+0.068	+1.199	<.001	<.001	3	13
SOFT_TISSUE	mRNA alternative polyadenylation →	+0.079	+1.105	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,684 associations by consensus.

RNA catabolic process by ZNF589 expression — BONE

Explore this box plot interactively →