Across TCGA patient cohorts, ZNF587 mutation is significantly associated with the RNA expression of many other genes, with 1,180 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF587-associated genes across cancer lineages are RPS15AP27, RNU6-1163P, and RNA5SP394. Each is linked with ZNF587 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF587-to-partner and partner-to-ZNF587 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF587→partner) and Y-score (partner→ZNF587) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RPS15AP27 →	+0.150	+4.448	.003	.006	3	3
BLCA	RNU6-1163P →	+0.181	+4.018	<.001	.001	3	2
CESC	RNA5SP394 →	+0.360	+5.345	<.001	.001	3	2
CESC	RNU4-31P →	+0.301	+4.874	<.001	.002	3	2
CESC	STAU2P1 →	+0.070	+4.364	.005	.006	3	2
CESC	RN7SL97P →	+0.189	+5.144	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,180 associations by consensus.

Exploration

ZNF587 survival (RNA) · tumor vs normal (RNA) · all ZNF587 data types