ZNF587

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF587 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF587-associated genes across cancer lineages are eEF2, GATA3, and mTOR_pS2448. Each is linked with ZNF587 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF587-to-partner and partner-to-ZNF587 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF587→partner) and Y-score (partner→ZNF587) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECeEF2 →+0.516+3.459<.001.00532
UCECGATA3 →+0.156+1.820.046.01632
UCECmTOR_pS2448 →-0.177-2.565.004.01032
UCECp62 Lck ligand →+0.360+1.807.007.02732
UCECPKC-delta_pS664 →-0.153-3.321.001.00932
UCECPKC-b-II_pS660 →-0.284-2.321.012.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

Exploration