ZNF585B

Across TCGA patient cohorts, ZNF585B mutation is significantly associated with the RNA expression of many other genes, with 5,228 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF585B-associated genes across cancer lineages are FKBP4P8, SLC25A5P9, and OR4K6P. Each is linked with ZNF585B in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF585B-to-partner and partner-to-ZNF585B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FKBP4P8 grouped by ZNF585B-low versus ZNF585B-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF585B→partner) and Y-score (partner→ZNF585B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FKBP4P8 →	+0.033	+5.215	<.001	.003	3	3
READ	SLC25A5P9 →	+0.135	+3.724	.001	.007	3	3
LUSC	OR4K6P →	+0.226	+4.520	<.001	.004	3	3
LUSC	MIR4527 →	+0.552	+4.295	<.001	.006	3	3
STAD	RNU6-1090P →	+0.380	+3.330	<.001	.008	3	3
STAD	RNA5SP223 →	+0.273	+3.267	.001	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,228 associations by consensus.

FKBP4P8 by ZNF585B expression — BRCA

Explore this box plot interactively →