ZNF585B

Across TCGA patient cohorts, ZNF585B mutation is significantly associated with the total protein of many other genes, with 59 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF585B-associated genes across cancer lineages are ASNS, CD31, and EGFR_pY1068. Each is linked with ZNF585B in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF585B-to-partner and partner-to-ZNF585B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by ZNF585B-low versus ZNF585B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF585B→partner) and Y-score (partner→ZNF585B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.426	+1.999	<.001	.002	3	3
SKCM	CD31 →	-0.130	-2.305	.021	.032	3	3
UCEC	EGFR_pY1068 →	-0.184	-1.502	.018	.027	3	2
SKCM	GAPDH →	+0.574	+1.999	.005	.002	3	2
UCEC	JNK_pT183_Y185 →	-0.181	-2.247	<.001	.001	3	2
UCEC	MEK1 →	+0.419	+2.999	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 59 associations by consensus.

ASNS by ZNF585B expression — UCEC

Explore this box plot interactively →