Across TCGA patient cohorts, ZNF583 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,490 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ZNF583-associated proteins across cancer lineages are CLPX, ABI2, and OAS2_S466. Each is linked with ZNF583 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF583-to-partner and partner-to-ZNF583 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF583→partner) and Y-score (partner→ZNF583) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CLPX →	-0.294	-0.313	.003	.006	3	6
LSCC	ABI2 →	+0.308	+0.377	<.001	.001	3	6
LSCC	OAS2_S466 →	-1.785	-0.499	<.001	.007	3	5
HNSC	ARHGAP31_S1432 →	+0.892	+0.591	<.001	.004	3	5
HNSC	ZSCAN18 →	+0.706	+0.665	<.001	<.001	3	5
BRCA	RRP1 →	-0.406	-0.499	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,490 associations by consensus.

Exploration

ZNF583 survival (RNA) · tumor vs normal (RNA) · all ZNF583 data types