Across TCGA cell cohorts, ZNF583 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,448 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF583-associated GO terms across cancer lineages are Cell division, Regulation of hematopoietic stem cell differentiation, and G1/S transition of mitotic cell cycle. Each is linked with ZNF583 in more than 10 cancer types. Because this analysis shows association rather than direction, both ZNF583-to-partner and partner-to-ZNF583 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF583→partner) and Y-score (partner→ZNF583) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Cell division →	+0.081	+1.311	<.001	<.001	3	11
LUNG_SCLC	Regulation of hematopoietic stem cell differentiation →	+0.097	+0.971	<.001	.004	2	10
BREAST	G1/S transition of mitotic cell cycle →	+0.040	+0.808	.001	.004	2	10
LUNG_SCLC	Regulation of double-strand break repair →	+0.061	+0.788	<.001	.006	2	9
LUNG_SCLC	Mitotic cytokinesis →	+0.101	+1.179	<.001	<.001	3	8
BLOOD_Leukemia	Regulation of G1/S transition of mitotic cell cycle →	+0.061	+0.576	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,448 associations by consensus.

Exploration

ZNF583 survival (RNA) · tumor vs normal (RNA) · all ZNF583 data types