Across TCGA patient cohorts, ZNF580 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,890 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF580-associated proteins across cancer lineages are VEZF1, NFYA_S326, and MYEF2. Each is linked with ZNF580 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF580-to-partner and partner-to-ZNF580 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF580→partner) and Y-score (partner→ZNF580) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	VEZF1 →	+0.463	+0.448	<.001	<.001	3	4
PDAC	NFYA_S326 →	+0.713	+0.297	.002	.002	3	4
HNSC	MYEF2 →	+0.894	+0.602	<.001	<.001	3	4
GBM	THYN1 →	+0.421	+0.575	<.001	<.001	3	4
PDAC	TOP2B_S1400 →	+0.603	+0.325	<.001	<.001	3	4
BRCA	ARHGAP35 →	+0.371	+0.617	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,890 associations by consensus.

Exploration

ZNF580 survival (RNA) · tumor vs normal (RNA) · all ZNF580 data types