Across TCGA pan-cancer cohorts, ZNF579 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ZNF579 data layer compared with 27 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher ZNF579 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ZNF579 expression acts as an unfavorable survival marker.

ESCA and STAD are the cancer types where ZNF579 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Median	II,III,IV	0.103	0.868	<.001	12	view →
STAD	OS	Median	II,III,IV	0.183	0.660	.009	12	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: ZNF579 tumor-vs-normal RNA expression · all ZNF579 data types