Across TCGA patient cohorts, ZNF579 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,394 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF579-associated proteins across cancer lineages are TRIM28, USP39, and XPO1. Each is linked with ZNF579 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF579-to-partner and partner-to-ZNF579 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF579→partner) and Y-score (partner→ZNF579) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TRIM28 →	+0.466	+0.659	<.001	<.001	3	5
GBM	USP39 →	+0.308	+0.630	<.001	<.001	3	4
LSCC	XPO1 →	+0.256	+0.402	<.001	.002	3	4
GBM	PRPF31 →	+0.296	+0.577	<.001	<.001	3	4
LSCC	MSH6 →	+0.485	+0.460	.001	<.001	3	4
LSCC	PNKP →	+0.299	+0.596	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,394 associations by consensus.

Exploration

ZNF579 survival (RNA) · tumor vs normal (RNA) · all ZNF579 data types