Across TCGA patient cohorts, ZNF579 mutation is significantly associated with the RNA expression of many other genes, with 311 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF579-associated genes across cancer lineages are RNA5SP146, FAM47A, and RNU1-62P. Each is linked with ZNF579 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF579-to-partner and partner-to-ZNF579 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF579→partner) and Y-score (partner→ZNF579) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNA5SP146 →	+0.562	+5.542	<.001	<.001	3	2
CESC	FAM47A →	+0.048	+5.306	<.001	.006	3	1
CESC	RNU1-62P →	+0.312	+5.539	<.001	.004	3	1
CESC	RNU6-912P →	+0.337	+5.010	<.001	.009	3	1
CESC	LIN28AP2 →	+0.157	+5.103	<.001	.008	3	1
CESC	ALDH7A1P2 →	+0.067	+5.539	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 311 associations by consensus.

Exploration

ZNF579 survival (RNA) · tumor vs normal (RNA) · all ZNF579 data types