Across TCGA cell cohorts, ZNF579 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,315 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF579-associated GO terms across cancer lineages are Negative regulation of calcium ion export across plasma membrane, Regulation of protein localization to endoplasmic reticulum, and Negative regulation of DNA-templated transcription, elongation. Each is linked with ZNF579 in more than 17 cancer types. Because this analysis shows association rather than direction, both ZNF579-to-partner and partner-to-ZNF579 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF579→partner) and Y-score (partner→ZNF579) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of calcium ion export across plasma membrane →	+0.087	+0.905	.001	.001	3	18
KIDNEY	Regulation of protein localization to endoplasmic reticulum →	+0.115	+0.759	.003	.008	3	15
STOMACH	Negative regulation of DNA-templated transcription, elongation →	+0.121	+0.988	.008	.004	3	15
BONE	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.169	+1.361	<.001	<.001	3	15
BONE	Negative regulation of mRNA splicing, via spliceosome →	+0.090	+1.284	<.001	<.001	3	15
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.185	+1.055	.001	.003	2	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,315 associations by consensus.

Exploration

ZNF579 survival (RNA) · tumor vs normal (RNA) · all ZNF579 data types