Across TCGA cell cohorts, ZNF579 mutation is significantly associated with the RNA expression of many other genes, with 472 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF579-associated genes across cancer lineages are CCDC117, TMEM81, and CENPVL3. Each is linked with ZNF579 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF579-to-partner and partner-to-ZNF579 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF579→partner) and Y-score (partner→ZNF579) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CCDC117 →	+0.582	+3.451	.005	.002	3	2
LARGE_INTESTINE	TMEM81 →	+0.524	+3.169	<.001	.009	3	2
LARGE_INTESTINE	CENPVL3 →	+0.148	+2.183	<.001	.007	3	2
PANCREAS	OPN1MW3 →	+0.013	+5.614	<.001	.002	3	1
OESOPHAGUS	OR2T2 →	+0.006	+4.906	<.001	.006	3	1
OESOPHAGUS	CSNKA2IP →	+0.036	+4.906	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 472 associations by consensus.

Exploration

ZNF579 survival (RNA) · tumor vs normal (RNA) · all ZNF579 data types