ZNF578

Across TCGA patient cohorts, ZNF578 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,927 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF578-associated proteins across cancer lineages are MRPL52, MCAM, and CEP170. Each is linked with ZNF578 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF578-to-partner and partner-to-ZNF578 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF578 versus MRPL52 in OV, with a Pearson correlation of -0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF578→partner) and Y-score (partner→ZNF578) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MRPL52 →	-0.438	-0.573	.003	.008	3	5
UCEC	MCAM →	+0.514	+1.043	<.001	<.001	3	4
GBM	CEP170 →	+0.252	+0.852	.001	<.001	3	4
LUAD	PPIB →	-0.380	-0.456	<.001	<.001	3	4
UCEC	SGCE →	+0.422	+0.719	<.001	.008	3	4
GBM	DNAJC3 →	-0.306	-0.880	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,927 associations by consensus.

ZNF578 vs MRPL52 — OV

Explore this scatter interactively →