ZNF576

Across TCGA pan-cancer cohorts, ZNF576 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ZNF576 data layer compared with 20 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher ZNF576 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated ZNF576 expression acts as an unfavorable survival marker.

GBM and LSCC are the cancer types where ZNF576 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	OS	Quartile	All	0.664	0.913	.022	4	view →
LSCC	DFS	Median	II,III,IV	0.558	0.852	.028	3	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

ZNF576–GBM (OS)

Open the GBM breakdown →