ZNF576

Across TCGA patient cohorts, ZNF576 protein abundance is significantly associated with the RNA expression of many other genes, with 1,606 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF576-associated genes across cancer lineages are PTX3, SNRNP48, and APMAP. Each is linked with ZNF576 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF576-to-partner and partner-to-ZNF576 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF576 versus PTX3 in BRCA, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF576→partner) and Y-score (partner→ZNF576) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PTX3 →	+2.949	+0.553	.004	.002	3	2
UCEC	SNRNP48 →	+0.626	+0.716	.009	<.001	3	2
BRCA	APMAP →	-0.946	-0.431	.004	.001	3	2
BRCA	TEX10 →	+0.749	+0.432	.002	.006	3	2
BRCA	POLR1E →	+1.446	+0.697	.002	.001	3	2
BRCA	MRPS18C →	+0.487	+0.491	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,606 associations by consensus.

ZNF576 vs PTX3 — BRCA

Explore this scatter interactively →