ZNF576

Across TCGA patient cohorts, ZNF576 mutation is significantly associated with the RNA expression of many other genes, with 69 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF576-associated genes across cancer lineages are RNU5E-9P, RPLP1P10, and MIR6514. Each is linked with ZNF576 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF576-to-partner and partner-to-ZNF576 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU5E-9P grouped by ZNF576-low versus ZNF576-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF576→partner) and Y-score (partner→ZNF576) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU5E-9P →	+0.366	+4.662	<.001	.003	3	2
HNSC	RPLP1P10 →	+0.117	+5.505	<.001	.004	3	2
UCEC	MIR6514 →	+0.908	+3.460	.004	.005	3	1
HNSC	MIRLET7A2 →	+0.644	+5.912	<.001	.002	3	1
HNSC	RNU6-520P →	+0.337	+5.368	<.001	.005	3	1
HNSC	LINC01078 →	+0.112	+5.368	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 69 associations by consensus.

RNU5E-9P by ZNF576 expression — UCEC

Explore this box plot interactively →