ZNF576

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF576 mutation is significantly associated with the total protein of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF576-associated genes across cancer lineages are p90 RSK. Each is linked with ZNF576 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF576-to-partner and partner-to-ZNF576 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p90 RSK grouped by ZNF576-low versus ZNF576-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF576→partner) and Y-score (partner→ZNF576) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECp90 RSK →+0.341+2.820.003.03621
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

p90 RSK by ZNF576 expression — UCEC

Box plot of p90 RSK in ZNF576-low vs ZNF576-high samples in UCEC.

Explore this box plot interactively →

Exploration