ZNF576

Across TCGA cell cohorts, ZNF576 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,414 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF576-associated GO terms across cancer lineages are Negative regulation of calcium ion export across plasma membrane, DNA strand elongation involved in DNA replication, and Regulation of anaphase-promoting complex-dependent catabolic process. Each is linked with ZNF576 in more than 11 cancer types. Because this analysis shows association rather than direction, both ZNF576-to-partner and partner-to-ZNF576 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of calcium ion export across plasma membrane grouped by ZNF576-low versus ZNF576-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF576→partner) and Y-score (partner→ZNF576) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Negative regulation of calcium ion export across plasma membrane →	+0.083	+0.639	<.001	<.001	3	12
BLOOD_Lymphoma	DNA strand elongation involved in DNA replication →	+0.134	+0.740	<.001	<.001	3	11
LARGE_INTESTINE	Regulation of anaphase-promoting complex-dependent catabolic process →	+0.124	+0.702	<.001	<.001	3	11
BLOOD_Lymphoma	Nucleosome disassembly →	+0.165	+0.934	<.001	<.001	3	11
PANCREAS	Peptidyl-proline modification →	+0.156	+0.546	<.001	<.001	3	10
SOFT_TISSUE	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.112	+0.642	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,414 associations by consensus.

Negative regulation of calcium ion export across plasma membrane by ZNF576 expression — CNS

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