ZNF574

Across TCGA patient cohorts, ZNF574 protein abundance is significantly associated with the RNA expression of many other genes, with 12,120 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF574-associated genes across cancer lineages are ZNF227, ZNF180, and FBL. Each is linked with ZNF574 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF574-to-partner and partner-to-ZNF574 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF574 versus ZNF227 in BRCA, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF574→partner) and Y-score (partner→ZNF574) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ZNF227 →	+0.626	+0.344	<.001	<.001	3	6
BRCA	ZNF180 →	+0.722	+0.347	<.001	<.001	3	6
HNSC	FBL →	+0.830	+0.288	.002	<.001	3	5
HNSC	ZNF567 →	+0.718	+0.315	.006	.004	3	5
GBM	BRIP1 →	+0.695	+0.303	<.001	<.001	3	5
HNSC	ZNF766 →	+0.439	+0.265	.002	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,120 associations by consensus.

ZNF574 vs ZNF227 — BRCA

Explore this scatter interactively →