ZNF574

Across TCGA cell cohorts, ZNF574 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF574-associated genes across cancer lineages are C18orf63, OR6V1, and S100A7A. Each is linked with ZNF574 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF574-to-partner and partner-to-ZNF574 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C18orf63 grouped by ZNF574-low versus ZNF574-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF574→partner) and Y-score (partner→ZNF574) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	C18orf63 →	+0.019	+4.867	<.001	.009	3	2
LARGE_INTESTINE	OR6V1 →	+0.022	+2.882	<.001	.005	3	2
BLOOD_Lymphoma	S100A7A →	+0.056	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	IFNL3 →	+0.100	+5.209	.001	.005	3	1
LARGE_INTESTINE	RIPPLY2 →	+0.404	+2.933	<.001	.003	3	1
LARGE_INTESTINE	OR11A1 →	+0.011	+3.240	.004	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

C18orf63 by ZNF574 expression — BLOOD_Lymphoma

Explore this box plot interactively →