Across TCGA pan-cancer cohorts, ZNF573 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated ZNF573 data layer compared with 25 for mass-spec protein.
The strongest signal is observed in colon adenocarcinoma (COAD), where higher ZNF573 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ZNF573 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.
COAD, UCEC, and LUAD are the cancer types where ZNF573 Mutation most reproducibly stratifies survival.
Mutation survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.