ZNF572

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZNF572 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF572-associated genes across cancer lineages are IFNA1, PABPC1L2A, and SPATA31A1. Each is linked with ZNF572 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF572-to-partner and partner-to-ZNF572 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNA1 grouped by ZNF572-low versus ZNF572-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF572→partner) and Y-score (partner→ZNF572) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_MyelomaIFNA1 →+0.030+4.807<.001.00631
BLOOD_LymphomaPABPC1L2A →+0.024+4.643<.001.00531
BLOOD_LymphomaSPATA31A1 →+0.057+4.191<.001.00731
BLOOD_LymphomaUSP17L1 →+0.019+4.191<.001.00731
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

IFNA1 by ZNF572 expression — BLOOD_Myeloma

Box plot of IFNA1 in ZNF572-low vs ZNF572-high samples in BLOOD_Myeloma.

Explore this box plot interactively →

Exploration