ZNF571

Across TCGA cell cohorts, ZNF571 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF571-associated genes across cancer lineages are RPF1, SSMEM1, and REG1B. Each is linked with ZNF571 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF571-to-partner and partner-to-ZNF571 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPF1 grouped by ZNF571-low versus ZNF571-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF571→partner) and Y-score (partner→ZNF571) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	RPF1 →	+0.644	+3.087	.006	.006	3	1
LARGE_INTESTINE	SSMEM1 →	+0.017	+2.444	.009	.008	3	1
LARGE_INTESTINE	REG1B →	+1.967	+2.518	<.001	.006	3	1
LARGE_INTESTINE	LINGO4 →	+0.102	+2.869	.003	.008	3	1
BLOOD_Leukemia	KRTAP4-4 →	+0.020	+5.569	<.001	.001	3	1
BLOOD_Leukemia	KIAA1210 →	+0.071	+4.551	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

RPF1 by ZNF571 expression — LARGE_INTESTINE

Explore this box plot interactively →