ZNF570

Across TCGA patient cohorts, ZNF570 mutation is significantly associated with the RNA expression of many other genes, with 2,113 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF570-associated genes across cancer lineages are SNORD116-3, RNA5SP412, and RNA5SP413. Each is linked with ZNF570 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF570-to-partner and partner-to-ZNF570 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD116-3 grouped by ZNF570-low versus ZNF570-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF570→partner) and Y-score (partner→ZNF570) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	SNORD116-3 →	+0.749	+5.103	<.001	.008	3	3
UCEC	RNA5SP412 →	+0.712	+2.588	<.001	<.001	3	3
UCEC	RNA5SP413 →	+1.129	+1.898	<.001	.002	3	3
READ	MIR6738 →	+1.071	+4.361	<.001	.006	3	2
STAD	RPL7AP23 →	+0.152	+3.979	<.001	.006	3	2
READ	MIR4729 →	+0.926	+4.653	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,113 associations by consensus.

SNORD116-3 by ZNF570 expression — CESC

Explore this box plot interactively →