ZNF570

Across TCGA cell cohorts, ZNF570 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,500 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF570-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Negative regulation of myoblast fusion, and Regulation of organelle assembly. Each is linked with ZNF570 in more than 13 cancer types. Because this analysis shows association rather than direction, both ZNF570-to-partner and partner-to-ZNF570 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by ZNF570-low versus ZNF570-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF570→partner) and Y-score (partner→ZNF570) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.096	+0.889	.006	.003	3	14
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.097	+0.889	.007	.003	3	13
OESOPHAGUS	Regulation of organelle assembly →	+0.038	+0.874	.003	.003	3	12
BREAST	Regulation of syncytium formation by plasma membrane fusion →	+0.078	+0.863	.001	.007	3	12
OVARY	Nucleocytoplasmic transport →	+0.068	+1.049	<.001	<.001	3	11
OVARY	RNA splicing, via transesterification reactions →	+0.061	+0.939	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,500 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by ZNF570 expression — OESOPHAGUS

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