ZNF57

Across TCGA cell cohorts, ZNF57 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,788 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ZNF57-associated GO terms across cancer lineages are Mitochondrial gene expression, Regulation of postsynapse organization, and Substrate adhesion-dependent cell spreading. Each is linked with ZNF57 in more than 8 cancer types. Because this analysis shows association rather than direction, both ZNF57-to-partner and partner-to-ZNF57 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial gene expression grouped by ZNF57-low versus ZNF57-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF57→partner) and Y-score (partner→ZNF57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Mitochondrial gene expression →	+0.115	+0.528	<.001	.001	3	9
BONE	Regulation of postsynapse organization →	-0.054	-0.512	.001	.004	3	8
CNS	Substrate adhesion-dependent cell spreading →	-0.101	-0.435	<.001	.001	3	8
SOFT_TISSUE	Regulation of G2/MI transition of meiotic cell cycle →	+0.066	+0.582	<.001	<.001	3	7
OVARY	Positive regulation of cyclin-dependent protein kinase activity →	-0.149	-0.520	.003	.009	2	8
OESOPHAGUS	Succinyl-CoA metabolic process →	+0.120	+0.448	.004	.005	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,788 associations by consensus.

Mitochondrial gene expression by ZNF57 expression — BONE

Explore this box plot interactively →