Across TCGA patient cohorts, ZNF569 mutation is significantly associated with the RNA expression of many other genes, with 5,688 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF569-associated genes across cancer lineages are WDR4, COX10, and GNPNAT1. Each is linked with ZNF569 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF569-to-partner and partner-to-ZNF569 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF569→partner) and Y-score (partner→ZNF569) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	WDR4 →	+0.352	+1.823	.001	.002	3	3
UCEC	COX10 →	+0.493	+2.000	<.001	<.001	3	3
UCEC	GNPNAT1 →	+0.646	+1.794	<.001	<.001	3	3
UCEC	CEP76 →	+0.462	+1.794	<.001	<.001	3	3
UCEC	FANCE →	+0.446	+1.617	.001	<.001	3	3
UCEC	EMC6 →	+0.559	+2.000	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,688 associations by consensus.

Exploration

ZNF569 survival (RNA) · tumor vs normal (RNA) · all ZNF569 data types