Across TCGA patient cohorts, ZNF569 mutation is significantly associated with the total protein of many other genes, with 65 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF569-associated genes across cancer lineages are TFRC, ASNS, and ATM. Each is linked with ZNF569 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF569-to-partner and partner-to-ZNF569 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF569→partner) and Y-score (partner→ZNF569) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TFRC →	+0.452	+2.807	.004	.002	3	3
UCEC	ASNS →	+0.467	+2.247	<.001	.001	3	3
UCEC	ATM →	-0.371	-2.102	.006	.016	3	3
SKCM	p53 →	+0.296	+2.820	<.001	.035	3	3
STAD	GAPDH →	+0.387	+3.000	.029	.036	3	2
STAD	ACVRL1 →	-0.225	-2.978	.044	.036	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 65 associations by consensus.

Exploration

ZNF569 survival (RNA) · tumor vs normal (RNA) · all ZNF569 data types