Across TCGA cell cohorts, ZNF569 mutation is significantly associated with the RNA expression of many other genes, with 167 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF569-associated genes across cancer lineages are C6orf118, GH2, and BPIFB6. Each is linked with ZNF569 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF569-to-partner and partner-to-ZNF569 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF569→partner) and Y-score (partner→ZNF569) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C6orf118 →	+0.115	+2.378	<.001	.006	3	2
BLOOD_Leukemia	GH2 →	+0.014	+3.969	<.001	.009	3	2
BLOOD_Leukemia	BPIFB6 →	+0.031	+3.969	<.001	.009	3	2
URINARY_TRACT	RNASE9 →	+0.016	+5.087	<.001	.004	3	1
LARGE_INTESTINE	PDE10A →	+0.980	+3.212	.001	.006	3	1
LARGE_INTESTINE	NDUFAF4 →	+0.633	+3.212	.003	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 167 associations by consensus.

Exploration

ZNF569 survival (RNA) · tumor vs normal (RNA) · all ZNF569 data types