Across TCGA patient cohorts, ZNF568 mutation is significantly associated with the RNA expression of many other genes, with 6,716 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF568-associated genes across cancer lineages are RN7SL596P, UBE2CP4, and HMGN2P47. Each is linked with ZNF568 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF568-to-partner and partner-to-ZNF568 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF568→partner) and Y-score (partner→ZNF568) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RN7SL596P →	+0.271	+4.863	<.001	<.001	3	4
LUAD	UBE2CP4 →	+0.166	+3.514	<.001	.005	3	3
HNSC	HMGN2P47 →	+0.210	+3.862	<.001	.004	3	3
UCEC	SLC25A17 →	+0.362	+1.680	<.001	<.001	3	3
UCEC	PGK1 →	+0.739	+1.669	<.001	<.001	3	3
UCEC	MLX →	+0.543	+1.847	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,716 associations by consensus.

Exploration

ZNF568 survival (RNA) · tumor vs normal (RNA) · all ZNF568 data types