Across TCGA patient cohorts, ZNF568 mutation is significantly associated with the total protein of many other genes, with 45 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF568-associated genes across cancer lineages are ATM, N-Ras, and p38-MAPK_pT180_Y182. Each is linked with ZNF568 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF568-to-partner and partner-to-ZNF568 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF568→partner) and Y-score (partner→ZNF568) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.366	-2.687	.006	.005	3	3
UCEC	N-Ras →	-0.108	-1.565	.002	.008	3	2
UCEC	p38-MAPK_pT180_Y182 →	-0.295	-1.227	.025	.015	3	2
UCEC	Shc_pY317 →	-0.189	-1.857	<.001	<.001	3	2
UCEC	Cyclin-B1 →	+0.604	+1.637	<.001	.001	3	2
UCEC	14-3-3_beta →	-0.096	-1.227	.001	.015	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

Exploration

ZNF568 survival (RNA) · tumor vs normal (RNA) · all ZNF568 data types