ZNF564

Across TCGA cell cohorts, ZNF564 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF564-associated genes across cancer lineages are C2CD4B, ADAM2, and ITIH6. Each is linked with ZNF564 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF564-to-partner and partner-to-ZNF564 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C2CD4B grouped by ZNF564-low versus ZNF564-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF564→partner) and Y-score (partner→ZNF564) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	C2CD4B →	+1.241	+3.847	<.001	.004	3	2
LUNG_NSCLC_LUAD	ADAM2 →	+0.075	+4.734	<.001	.002	3	1
BLOOD_Leukemia	ITIH6 →	+0.019	+4.754	<.001	.002	3	1
BLOOD_Leukemia	SLITRK3 →	+0.029	+3.289	<.001	.009	3	1
BLOOD_Leukemia	CYP39A1 →	+0.127	+4.091	.001	.002	3	1
BLOOD_Leukemia	CYP26C1 →	+0.073	+4.047	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

C2CD4B by ZNF564 expression — BLOOD_Leukemia

Explore this box plot interactively →