ZNF562

Across TCGA pan-cancer cohorts, ZNF562 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ZNF562 data layer compared with 26 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ZNF562 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated ZNF562 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LSCC show a favorable association.

HNSC, UCEC, and LSCC are the cancer types where ZNF562 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	II,III,IV	0.559	0.916	.008	14	view →
UCEC	DFS	Quartile	All	1.000	0.357	.040	8	view →
LSCC	DFS	Tertile	All	1.000	0.920	.025	8	view →
GBM	DFS	Median	All	0.247	0.500	.015	7	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ZNF562–HNSC (OS)

Open the HNSC breakdown →